In fantasy football, a handcuff is a player who is second string to a starter that will be first up if an injury occurs. Here are our RB handcuff rankings for 2021.
- Kareem hunt CLE (Nick Chubb)
- John Connor ARZ (Chase Edmonds)
- Trey Sermon SFF (Raheem Mohstert)
- AJ Dillon GBP (Aaron Jones)
- Gus Edwards BAL (JK Dobbins)
- Kenyan Drake LVR (Josh Jacobs)
- Jamal Williams DET (Deandre Swift)
- Tony Pollard DAL (Zeke Elliott)
- Phillip Lindsay Hou (David Johnson)
- James White NEP (Sony Michel)
